Stereoselective synthesis of aryl cyclopentene scaffolds by heck–matsuda desymmetrization of 3-cyclopentenol
Ricardo A. Angnes, Juliana M. Oliveira, Caio C. Oliveira, Nelson C. Martins, Carlos Roque D. Correia
ARTIGO
Inglês
Agradecimentos: Financial support was provided by the S¼o Paulo Research Foundation - Fapesp (2011/23832-6; 2013/07600-3). We are also grateful to Dr. Cristiane Schwalm for her help with the X-ray diffraction
Abstract: Breaking the symmetry! The desymmetrization of 3-cyclopentenol was achieved using an enantioselective intermolecular Heck–Matsuda reaction, allowing the construction of synthetically useful chiral five-membered scaffolds in good yields and excellent enantiomeric excesses (see scheme). This...
Ver mais
Abstract: Breaking the symmetry! The desymmetrization of 3-cyclopentenol was achieved using an enantioselective intermolecular Heck–Matsuda reaction, allowing the construction of synthetically useful chiral five-membered scaffolds in good yields and excellent enantiomeric excesses (see scheme). This easy route to densely functionalized cis-1,4-arylcyclopentenols provides new opportunities for enantioselective synthesis
Ver menos
Fechado
Stereoselective synthesis of aryl cyclopentene scaffolds by heck–matsuda desymmetrization of 3-cyclopentenol
Ricardo A. Angnes, Juliana M. Oliveira, Caio C. Oliveira, Nelson C. Martins, Carlos Roque D. Correia
Stereoselective synthesis of aryl cyclopentene scaffolds by heck–matsuda desymmetrization of 3-cyclopentenol
Ricardo A. Angnes, Juliana M. Oliveira, Caio C. Oliveira, Nelson C. Martins, Carlos Roque D. Correia
Fontes
|
Chemistry: a european journal Vol. 20, n. 41 (Oct., 2014), p. 13117-13121 |