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Synthesis, characterization and in vitro biological assays of a silver(I) complex with 5-fluorouracil : a strategy to overcome multidrug resistant tumor cells

Synthesis, characterization and in vitro biological assays of a silver(I) complex with 5-fluorouracil : a strategy to overcome multidrug resistant tumor cells

Julia H. Bormio Nunes, Fernando R.G. Bergamini, Wilton R. Lustri, Paula P. de Paiva, Ana Lúcia T.G. Ruiz, João Ernesto de Carvalho, Pedro P. Corbi

ARTIGO

Inglês

Agradecimentos: This study was supported by grants from Brazilian Agencies FAPESP (São Paulo State Research Council, grant # 2015/25114-4) CAPES (Coordination for the Improvement of Higher Level Personnel) andCNPq (National Council for Scientific and Technological Develo

A silver(I) complex with the antitumor drug 5-fluorouracil was synthesized and characterized by a set of chemical and spectroscopic techniques. Elemental, thermogravimetric and mass spectrometric analyses indicate a 3:2 metal/ligand composition, with mini

CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ

442123/2014-0

COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP

2015/25114-4

Fechado

Ensaios antibacterianos
Atividade antitumoral
Complexos metálicos
5-Fluorouracil
Artigo original

DOI:

Texto completo:

Synthesis, characterization and in vitro biological assays of a silver(I) complex with 5-fluorouracil : a strategy to overcome multidrug resistant tumor cells

Julia H. Bormio Nunes, Fernando R.G. Bergamini, Wilton R. Lustri, Paula P. de Paiva, Ana Lúcia T.G. Ruiz, João Ernesto de Carvalho, Pedro P. Corbi 

										

											
											
										

									

									

										

											

												
Synthesis, characterization and in vitro biological assays of a silver(I) complex with 5-fluorouracil : a strategy to overcome multidrug resistant tumor cells

											

												

														

		

							

					Julia H. Bormio Nunes, Fernando R.G. Bergamini, Wilton R. Lustri, Paula P. de Paiva, Ana Lúcia T.G. Ruiz, João Ernesto de Carvalho, Pedro P. Corbi
				

		

	


												

										

										
    
										
    
											
										
    
									
    
								
    
							
    
						
    
					
    
				
    
			
    
		
    
	
    
	

    

	

		
    
			
    
				
    
					
    
								
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Journal of fluorine chemistry (Fonte avulsa)