Agradecimentos: The Geant4-DNA project receives funding from the European Space Agency under contract number AO7146-4000107387/12/NL/AK (2013-2016). It is also supported by the INSERM PhysiCancer "MICRONAUTE" project (2013-2014). Thibault Andre was supported by a dedicated INSERM Canceropole Grand Sud Ouest funding for this work, under contract number 2012140602. Filippo Morini is post-doctoral fellow from the FWO at Hasselt University. M.A. Bernal thanks the FAPESP foundation in Brazil for financing his research activities through the 2011/51594-2 project Ver menos

Abstract: Monte Carlo simulations of S-values have been carried out with the Geant4-DNA extension of the Geant4 toolkit. The S-values have been simulated for monoenergetic electrons with energies ranging from 0.1 keV up to 20 keV, in liquid water spheres (for four radii, chosen between 10 nm and 1 mu m), and for electrons emitted by five isotopes of iodine (131, 132, 133, 134 and 135), in liquid water spheres of varying radius (from 15 mu m up to 250 mu m). The results have been compared to those obtained from other Monte Carlo codes and from other published data. The use of the Kolmogorov-Smirnov test has allowed confirming the statistical compatibility of all simulation results Ver menos