Chemical constituents of the volatile oil from leaves of annona coriacea and in vitro antiprotozoal activity
Carlos A. T. Siqueira, Jocimar Oliani, Adilson Sartoratto, Carmen L. Queiroga, Paulo R. H. Moreno, Juliana Q. Reimão, André G. Tempone, Dominique C. H. Fischer
ARTIGO
Inglês
The essential oil of the leaves from Annona coriacea Mart., Annonaceae, was extracted by hydrodistillation in a Clevenger apparatus and analyzed by GC/MS and GC/FID. The oil yield was 0.05% m/m. Sixty compounds were identified, in a complex mixture of sesquiterpenes (76.7%), monoterpenes (20.0%) and...
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The essential oil of the leaves from Annona coriacea Mart., Annonaceae, was extracted by hydrodistillation in a Clevenger apparatus and analyzed by GC/MS and GC/FID. The oil yield was 0.05% m/m. Sixty compounds were identified, in a complex mixture of sesquiterpenes (76.7%), monoterpenes (20.0%) and other constituents (3.3%). Bicyclogermacrene was its major compound (39.8%) followed by other sesquiterpenes. Most of the monoterpenes were in low concentration (<1%). Only β-pinene and pseudolimonene presented the highest level of 1.6%. The volatile oil presented anti-leishmanial and trypanocidal activity against promastigotes of four species of Leishmania and trypomastigotes of Trypanosoma cruzi, showing to be more active against Leishmania (L.) chagasi (IC50 39.93 µ g/mL) (95% CI 28.00-56.95 µ g/mL)
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COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP
Aberto
Chemical constituents of the volatile oil from leaves of annona coriacea and in vitro antiprotozoal activity
Carlos A. T. Siqueira, Jocimar Oliani, Adilson Sartoratto, Carmen L. Queiroga, Paulo R. H. Moreno, Juliana Q. Reimão, André G. Tempone, Dominique C. H. Fischer
Chemical constituents of the volatile oil from leaves of annona coriacea and in vitro antiprotozoal activity
Carlos A. T. Siqueira, Jocimar Oliani, Adilson Sartoratto, Carmen L. Queiroga, Paulo R. H. Moreno, Juliana Q. Reimão, André G. Tempone, Dominique C. H. Fischer
Fontes
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Revista brasileira de farmacognosia Vol. 21, no. 1 (Jan./Feb., 2010), p. 33-40 |