Three new diterpenoids from the leaves of Salvia lachnostachys
Cristhian Santos Oliveira, Carlos José Alvarez, Marcia Regina Pereira Cabral, Maria Helena Sarragiotto, Marcos José Salvador, Maria Élida Alves Stefanello
ARTIGO
Inglês
[3 new diterpenoids from the leaves of Salvia lachnostachys]
Agradecimentos: The authors are grateful to Élide P. Santos for collection and identification of the plant, to Carolina Calomeno (Design Department, UFPR) for the photograph of S. lachnostachys, to Fundação Araucária for financial support (process 38394/2014) and to CAPES (Finance Code 001), FAPESP...
Ver mais
Agradecimentos: The authors are grateful to Élide P. Santos for collection and identification of the plant, to Carolina Calomeno (Design Department, UFPR) for the photograph of S. lachnostachys, to Fundação Araucária for financial support (process 38394/2014) and to CAPES (Finance Code 001), FAPESP (process numbers 2006/06079-4, 2012/09101-1, 2015/03726-8 and 2017/03598-5), FAEPEX-UNICAMP and CNPq (process numbers #157952/2011-8, #311166/2016-4, #304266/2017-5, #427859/2018-2, and #309411/2019-0) for scholarships. This work was supported by Fundação Araucária (process 38394/2014)
Ver menos
Abstract: Three new diterpenoids, demethylfruticuline B (1), 20-hydroxyfruticuline B (2), and 6-hydroxyisofruticuline A (3) were isolated from the leaves of Salvia lachnostachys Benth, together with five known compounds: fruticuline B (4), fruticuline A (5), demethylfruticuline A (6),...
Ver mais
Abstract: Three new diterpenoids, demethylfruticuline B (1), 20-hydroxyfruticuline B (2), and 6-hydroxyisofruticuline A (3) were isolated from the leaves of Salvia lachnostachys Benth, together with five known compounds: fruticuline B (4), fruticuline A (5), demethylfruticuline A (6), heterobetulinic acid (7), and maslinic acid (8). The known compounds 7–8 are being reported for the first time in this species. Compounds 1 and 4–6 were tested for antioxidant activity using the ORAC-FL method, and the antioxidant capacity was measured as relative trolox equivalent. All compounds were active, with values of relative trolox equivalent varying between 1.20–2.42. The most active compound was demethylfruticuline B (1)
Ver menos
COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES
001
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP
2006/06079-4; 2012/09101-1; 2015/03726-8; 2017/03598-5
CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ
157952/2011-8; 311166/2016-4; 304266/2017-5; 427859/2018-2; 309411/2019-0
Fechado
Three new diterpenoids from the leaves of Salvia lachnostachys
Cristhian Santos Oliveira, Carlos José Alvarez, Marcia Regina Pereira Cabral, Maria Helena Sarragiotto, Marcos José Salvador, Maria Élida Alves Stefanello
Three new diterpenoids from the leaves of Salvia lachnostachys
Cristhian Santos Oliveira, Carlos José Alvarez, Marcia Regina Pereira Cabral, Maria Helena Sarragiotto, Marcos José Salvador, Maria Élida Alves Stefanello
Fontes
Natural product research (Fonte avulsa) |