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Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

B. Abou-Khalil, P. Auce, A. Avbersek, D.J. Bahlo M. Balding, L. Bast T. Baum, A.J. Becker, F. Becker, B. Berghuis, S.F. Berkovic, K.E. Boysen, J.P. Bradfield, L.C. Brody, R.J. Buono, E. Campbell, G.D. Cascino, C Catarino

ARTIGO

Inglês

The epilepsies affect around 65 million people worldwide and have a substantial missing heritability component. We report a genome-wide mega-analysis involving 15,212 individuals with epilepsy and 29,677 controls, which reveals 16 genome-wide significant

Aberto

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

B. Abou-Khalil, P. Auce, A. Avbersek, D.J. Bahlo M. Balding, L. Bast T. Baum, A.J. Becker, F. Becker, B. Berghuis, S.F. Berkovic, K.E. Boysen, J.P. Bradfield, L.C. Brody, R.J. Buono, E. Campbell, G.D. Cascino, C Catarino

										

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies

B. Abou-Khalil, P. Auce, A. Avbersek, D.J. Bahlo M. Balding, L. Bast T. Baum, A.J. Becker, F. Becker, B. Berghuis, S.F. Berkovic, K.E. Boysen, J.P. Bradfield, L.C. Brody, R.J. Buono, E. Campbell, G.D. Cascino, C Catarino

    Fontes

    Nature communications (Fonte avulsa)