Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: A Simple And Efficient New Approach To The Total Synthesis Of (±)-4- Amino-3-(4-chlorophenyl)-butyric Acid (baclofen)
Author: Coelho F.
De Azevedo M.B.M.
Boschiero R.
Resende P.
Abstract: Based on the utilization of a [2+21 cycloaddition reaction between dichloroketene and an appropriated olefin as a key step, we describe a new and simple four step approach to the total synthesis of (±)-4-amino-3-(4- chlorophenyl)-butyric acid (BACLOFEN), a selective GABA(B) agonist used as antispastic agent.
Rights: fechado
Identifier DOI: 
Date Issue: 1997
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
2-s2.0-0030958444.pdf293.68 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.