Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/99654
Type: Artigo de periódico
Title: Post-transfusional Hepatitis In The City Of Campinas, Sp, Brazil. Ii. Presence Of Anti-hbc And Anti-hcv Antibodies In Blood Donor Candidates And Occurrence Of Post-transfusional Hepatitis C In Recipients Of Blood Or Derivates [hepatites Pós-transfusionais Na Cidade De Campinas, Sp, Brasil. Ii. Presença Dos Anticorpos Anti-hbc E Anti-hcv Em Candidatos A Doadores De Sangue E Ocorrência De Hepatites Pós-transfusionais Pelo Vírus C Nos Receptores De Sangue Ou Derivados.]
Author: Goncales Junior F.L.
Pedro R.J.
da Silva L.J.
Boccato R.S.
Goncales N.S.
Abstract: We have analysed anti-HBc and anti-HCV antibodies in serum samples from 799 donors which had their blood or derivates transfused to 111 recipients. Anti-HBc and anti-HCV were reactive in respectively 9 and 2.1% of the donors tested. We have observed that among the 111 recipients, 44 had received at least one positive anti-HBc unit and 67 had been transfused only with negative anti-HBc, units. The risk of developing hepatitis C virus was 4.5 times higher for the recipients who received at least one positive anti-HBc unit. If the test for anti-HBc had been made for the blood donors in the serological screening, about 56% of the HCV cases in the recipients could have been avoided. The population of recipients who received at least one reacting unit of anti-HCV, presented a risk 29 times higher of developing this hepatitis, as compared to the transfused recipients with all anti-HCV negative units. Testing blood from donors for anti-HCV would avoid 79% of the post-transfusional HCV cases. Brazilian candidates to blood donors seem to be carriers either simultaneously or sequentially to hepatitis virus B and C, since 44.4% of the positive anti-HCV were also positive for anti-HBc. Testing for anti-HBc and anti-HCV in blood screening must be indicated in order to prevent post-transfusional hepatitis transmission in our community.
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Rights: aberto
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Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0027133679&partnerID=40&md5=db48251d129cf5abec0daf4992b28eb0
Date Issue: 1993
Appears in Collections:Unicamp - Artigos e Outros Documentos

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