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Type: Artigo de periódico
Title: Effect Of Gentamycin On Insulin Release And45ca Net Uptake By Isolated Islets
Author: Delattre E.
Santos M.L.
Boschero A.C.
Abstract: In isolated islets, gentamycin reduced both the45Ca net uptake and insulin release induced by glucose, but failed to inhibit the insulin secretion provoked by the combination of Ba2+ and theophylline. This indicates that the inhibitory effect of gentamycin is due to a reduction of Ca2+ entry into B-cells instead of to a harmful effect upon the integrity of the effector system, responsible for the extrusion of the insulin containing granules. © 1982 Birkhäuser Verlag.
Editor: Birkhäuser-Verlag
Rights: fechado
Identifier DOI: 10.1007/BF01954926
Date Issue: 1982
Appears in Collections:Unicamp - Artigos e Outros Documentos

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