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Type: Artigo de periódico
Title: Contraception With Long-acting Subdermal Implants. A Five-year Clinical Trial With Silastic Covered Rod Implants Containing Levonorgestrel
Author: Robertson D.N.
Diaz S.
Alvarez-Sanchez F.
Holma P.
Mishell D.R.
Coutinho E.
Brache V.
Croxatto H.B.
Paundes A.
Lacarra M.
Pavez M.
Roy S.
da Silva A.R.
Sivin I.
Stern J.
Abstract: A total of 189 women volunteered to accept subdermal implants for contraception. The implants were "covered rods", consisting of a core rod containing equal parts by weight of levonorgestrel and polydimethylsiloxane and sealed inside a thin-walled tube of Silastic tubing with medical adhesive. In one study 78 women used 4 3cm rods (study 07) and in the other 111 women used 6 3cm rods. In 5 years of use there were no pregnancies in either group. Terminations because of menstrual problems were twice as frequent among the 4-rod users than among users of the 6 rods. Menstrual pattern analysis is presented for the two rod regimens and compared with the previously reported patterns for the 6-capsule regimen (NORPLANTR). Long-term in vivo release rates are also presented. © 1985.
Rights: fechado
Identifier DOI: 10.1016/0010-7824(85)90003-4
Date Issue: 1985
Appears in Collections:Unicamp - Artigos e Outros Documentos

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