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Type: Artigo de periódico
Title: The Variable Region Of A Human Bence Jones Protein (jjo): Assignment To The V λ Iii Subgroup
Author: Marques M.R.F.
Marangoni S.
Oliveira B.
Abstract: Results from methanolysis of Bence Jones JJO protein followed by dinitrophenylation allowed us to identify seven DNP derivatives, one of them showing a clearly more intensive colour corresponding to di-DNP-tyrosine. These data indicated that protein JJO should not present PCA as an N-terminal residue. The knowledge that N-terminal tyrosine is a characteristic residue of V λ III domains allowed us to tentatively assign the BJP (JJO) variable region as a member of the V λ III sub type. Through Ouchterlony analysis Bence Jones (JJO) protein gives a spur over another λ protein (BJP Mau) using as reagent rabbit antiserum to BJP (JJO). These data could lead to a preliminary but inconclusive speculation that BJP (JJO) is associated with antigenic sub type St-III+ as described for other V λ III sub types.
Rights: fechado
Identifier DOI: 
Date Issue: 1987
Appears in Collections:Unicamp - Artigos e Outros Documentos

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