Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/97980
Type: Artigo
Title: Peripheral muscle glucose and potassium transport in a family with acanthosis nigricans and insulin resistance
Author: Saad, M.J.
Foss, M.C.
Abstract: This study was designed to determine the forearm exchange of glucose and potassium in four members of a family exhibiting acanthosis nigricans and insulin resistance. Total areas under the curves for potassium release or uptake were within the normal range in all patients. Peripheral glucose uptake, however, was normal in 3 patients and lower in one patient. In the latter patient, the dissociation observed between glucose and potassium transport suggests several manners of differential impairment of insulin action and/or steps distal to the insulin receptor as being responsible for insulin resistance.
This study was designed to determine the forearm exchange of glucose and potassium in four members of a family exhibiting acanthosis nigricans and insulin resistance. Total areas under the curves for potassium release or uptake were within the normal range in all patients. Peripheral glucose uptake, however, was normal in 3 patients and lower in one patient. In the latter patient, the dissociation observed between glucose and potassium transport suggests several manners of differential impairment of insulin action and/or steps distal to the insulin receptor as being responsible for insulin resistance
Subject: Glicose
Insulina
Country: Brasil
Editor: Associação Brasileira de Divulgação Científica
Citation: Brazilian Journal Of Medical And Biological Research. , v. 22, n. 6, p. 683 - 686, 1989.
Rights: fechado
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0024848418&partnerID=40&md5=fde41df3c878d12b72a9dbea18f82216
Date Issue: 1989
Appears in Collections:FCM - Artigos e Outros Documentos

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