Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/97832
Type: Artigo de periódico
Title: Decreased C-peptide Secretion In Sickle Cell Anemia
Author: Saad S.T.O.
Braga G.S.
Saad M.J.A.
Abstract: Intravenous glucose tolerance tests (IVGTT) were performed on 9 adults with sickle cell anemia and 15 normal controls. Blood samples were collected before and 1, 3, 5, 10, 20, 30, 40, 50, and 60 min after intravenous glucose infusion and used for glucose and C-peptide assays. The mean C-peptide concentration after glucose infusion was significantly (p<0.05) lower for the SCA patients as compared to the controls. No significant differences were observed in the glucose concentration of IVGTT between the two groups. These results suggest an inadequate insulin secretion by the endocrine pancreas in sickle cells anemia or an independent genetic abnormality in linkage desequilibrium with the β(s) gene.
Editor: 
Rights: fechado
Identifier DOI: 
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0024424195&partnerID=40&md5=23e06e3e29207a3c9f95b924afac4467
Date Issue: 1989
Appears in Collections:Unicamp - Artigos e Outros Documentos

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