Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/97830
Type: Artigo de periódico
Title: Bacterial Chemistry-iii: Preliminary Studies On Trypanosomal Activities Of Chromobacterium Violaceum Products.
Author: Duran N.
Campos V.
Riveros R.
Joyas A.
Pereira M.F.
Haun M.
Abstract: It has been found that the pigment-I from Chromobacterium violaceum, 3-[1,2-dihydro5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-yli diene] 1,3-dihydro-2H-indol-2-one, has trypanocide activity. The formylated derivatives, pigment-III, immobilized 100% of the Trypanosoma cruzi at a level of 46 microM after 48 h of interaction with a total growth inhibition in the same period. Pigment-I exhibited low toxicity and a DNA synthesis inhibition similar to that of Nifurtimox, a known trypanocide compound.
Editor: 
Rights: aberto
Identifier DOI: 
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0024624735&partnerID=40&md5=286471b12a7d86163e0ada542f2b23bc
Date Issue: 1989
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.