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Type: Artigo de periódico
Title: Carbon Nanotube Based Sensor For Simultaneous Determination Of Acetaminophen And Ascorbic Acid Exploiting Multiple Response Optimization And Measures In The Presence Of Surfactant
Author: Duarte E.H.
Kubota L.T.
Tarley C.R.T.
Abstract: A simple procedure for the simultaneous determination of acetaminophen (AC) and ascorbic acid (AA) by differential pulse voltammetry (DPV) using a carbon nanotube paste electrode exploiting measures in cetylpyridinium bromide (CPB) medium is described. Under the best instrumental parameters of DPV, optimized by means of factorial design, the calibration plots in the range 100.0-700.0μmolL-1 (r=0.993) and 39.4-146.3μmolL-1 (r=0.995) with limits of detection of 7.1 and 2.1μmolL-1, were achieved for AA and AC, respectively. The developed method was successfully applied for the AC and AA determination in pharmaceutical formulations, whose accuracy was attested by comparison with HPLC method. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Rights: fechado
Identifier DOI: 10.1002/elan.201200426
Date Issue: 2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

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