Please use this identifier to cite or link to this item:
Type: Artigo de periódico
Title: Optimal Chemotherapy: A Case Study With Drug Resistance, Saturation Effect, And Toxicity
Author: Costa M.I.S.
Boldrini J.L.
Bassanezi R.C.
Abstract: A system of differential equations for the control of tumour cell growth in a cyclenonspecific chemotherapy is presented. A rate-of-kill term of saturation type, drug resistance, and toxicity are taken into account in a class of optimal control problems. Some results are obtained for general tumour cell growth rates. A detailed analysis is presented for the Malthusian cell growth, which shows a variety of optimal treatments according to the values of the model parameters and initial tumour level. © 1994 Oxford University Press.
Rights: fechado
Identifier DOI: 10.1093/imammb/11.1.45
Date Issue: 1994
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.