Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/96207
Type: Artigo de periódico
Title: Bone Marrow Morphology In Patients With Neutropenia Due To Chronic Exposure To Organic Solvents (benzene): Early Lesions
Author: Ruiz M.A.
Augusto L.G.S.
Vassallo J.
Vigorito A.C.
Lorand-Metze I.
Souza C.A.
Abstract: The authors present the histological and cytological features of bone marrow (BMJ in 152 employees from the steel plant of Cubatao (S. Paulo-Brazil) who presented with neutropenia, due to chronic exposure to benzene and its homologues. All patients were male. Mean age was 35 years. At the time of this study, all patients were removed from risk areas because of the hematological abnormality. BM morphology was characterized by a hypocellular hemopoiesis (82%). Decrease of the granulocytic precursors (86%) was the most outstanding feature. Erythroid and megakaryocytic series were diminished in 40% and 57% of the cases, respectively. Eosinophilia in BM was observed in 71% of the cases. Cell atypias and stromal changes (necrosis, increase in reticulin fibres) were frequent.
Editor: 
Rights: fechado
Identifier DOI: 
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0028326950&partnerID=40&md5=e3dc51bd9287ca0a731ce02f9b2a2120
Date Issue: 1994
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.