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|Type:||Artigo de periódico|
|Title:||Expression Of Epstein-barr Virus In Classical Hodgkin's Lymphomas In Brazilian Adult Patients|
De Souza C.A.
|Abstract:||We studied the frequency of Epstein-Barr virus (EBV) expression in Hodgkin's lymphoma (HL) among 78 adult Brazilian patients and correlated it with clinical findings and survival. Latent membrane protein-1 (LMP-1) was detected by immunohistochemistry and EBV-encoded RNA (EBER) by in situ hybridization. EBV was expressed in 50 patients (64.1%), more frequently in those with mixed cellularity (MC). There was no relation between EBV expression and sex, age or stage of the disease. Expression of LMP-1 correlated with better overall survival (p = 0.02). EBV expression in adult patients with HL in our study was similar to that in other developing countries. Expression of LMP-1 was associated with better prognosis.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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