Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/95002
Type: Artigo de periódico
Title: Squamous And/or Glandular Differentiation In Urothelial Carcinoma: Prevalence And Significance In Transurethral Resections Of The Bladder
Author: Billis A.
Schenka A.A.
Ramos C.C.O.
Carneiro L.T.
Araujo V.
Abstract: Background: It is controversial if urothelial carcinoma of the bladder with squamous and/or glandular differentiation is a more aggressive neoplasm than conventional urothelial carcinoma. Design: A total of 165 transurethral resections of the bladder were reviewed. A group with squamous and/or glandular differentiation was compared to a group without this finding. The qui-square test was used to assess the association of the groups with stage (TNM, 1997). Results: Of the total of 165 transurethral resections of the bladder, 153 (92.72%) were conventional urothelial carcinomas and 12 (7.27%) showed squamous and/or glandular differentiation. The distribution according to stage was 84 (54.9%), 35 (22.9%) and 34 (22.2%) for the group without differentiation and 0 (0%), 3 (25%) and 9 (75%) for the group with squamous and/or glandular differentiation, respectively for stages pTa, pT1 and pT2. Tumors with squamous and/or glandular differentiation showed a significant statistical correlation to higher stage at clinical presentation (p < 0.0001). There was no significant statistical relation according to age (p = 0.8433), sex (p = 0.5672) or race (p = 0.3137). Conclusions: The results suggest that urothelial bladder carcinomas with squamous and/or glandular differentiation are more aggressive neoplasms. There was a significant statistical correlation between tumors with this differentiation and higher stage at clinical presentation.
Editor: 
Rights: fechado
Identifier DOI: 10.1023/A:1020597611645
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-0035779766&partnerID=40&md5=535769f799d2040c9b0e614c24b63740
Date Issue: 2001
Appears in Collections:Unicamp - Artigos e Outros Documentos

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