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Type: Artigo de periódico
Title: The Effects Of A Single Dose Of Sildenafil Citrate (viagra®) On The Retrobulbar Circulation And Visual Field [estudo Da Circulação Retrobulbar E Do Campo Visual Após Dose única Oral De Citrato De Sildenafil (viagra®)]
Author: Kurahashi A.
Nascimento M.
Marcondes A.M.
Filho N.M.
Baracat J.
Costa V.P.
Abstract: Purpose: To analyze the effects of 100 mg of sildenafil citrate (Viagra®) on the retrobulbar circulation and visual field. Methods: A double masked, placebo controlled study was conducted in 10 males with a mean age of 27.7 ± 5.68 years. The right eye of each volunteer underwent orbital color Doppler imaging and automated perimetry (Humphrey, program 30-2, Full-Threshold Strategy) at 3 occasions: baseline, 1 hour after placebo and 1 hour after 100 mg of sildenafil. The foveal threshold and the mean deviation (MD) were analyzed by automated perimetry on the three occasions. Color Doppler imaging allowed the measurement of the peak systolic velocity (PSV), end diastolic velocity (EDV) and Pourcelot index (PI) in the central retinal artery and ophthalmic artery. Results: The foveal threshold and the mean deviation did not show a significant change following the administration of sildenafil. The ophthalmic artery peak systolic velocity and end diastolic velocity significantly increased after the administration of sildenafil (p<0.001). The hemodynamic parameters in the central retinal artery and the ophthalmic artery PI did not significantly change. Conclusions: Sildefanil citrate increased the blood flow velocities in the ophthalmic artery in normal subjects, with no significant changes in the foveal threshold and mean deviation in the automated perimetry.
Rights: aberto
Identifier DOI: 
Date Issue: 2001
Appears in Collections:Unicamp - Artigos e Outros Documentos

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