Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/94514
Type: Artigo de periódico
Title: Determination Of Tetracyclines In Veterinarian Medicines By Flow Injection Analysis (fia) [determinação De Tetraciclinas Em Medicamentos Veterinários Utilizando Análise Por Injeção Em Fluxo (fia)]
Author: Silva Jr. L.S.
Rath S.
Reyes F.G.R.
Abstract: Flow injection analysis (FIA) coupled to fluorescence detection was employed for the determination of oxytetracycline (OTC), doxycicline (DC) and tetracycline (TC) in veterinarian drugs. The FIA system was optimized in relation to the carrier solvent (NaOH 2.5 10-3 mol L-1) and pump flow (0.5 mL min-1). The detector excitement and emission wavelengths were set at 420 nm and 530 nm, respectively. The method was validated by the evaluation of the following parameters: linear range (0.02 - 0.15 mg mL-1), linearity: r(OTC) 0.9975; r(DC) 0.9903; and r(TC) 0.9913; intra- and inter-assay accuracy (RSD <1.0% and <3.0%, respectively), detectability (120 ng), recovery (98 to 104%) and sampling frequency (50 injections h-1). It was verified a variation from 90 to 104% of the active ingredient related to the nominal amount informed in the bull of veterinarian drugs available in the market.
Editor: 
Rights: fechado
Identifier DOI: 
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-19544372104&partnerID=40&md5=a1573ffd127ed2bd2f41b2609f8ca532
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.