Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/94428
Type: Artigo de periódico
Title: Chemoenzymatic Syntheses Of (r)-2-bromo-, (r)2-chloro- And (r)2-azido-1-(1,3-benzodioxol-5-yl)-1-ethanol
Author: Antunes H.
Fardelone L.C.
Rodrigues J.A.R.
Moran P.J.S.
Abstract: Enantioselective reductions of 2-X-1-(1,3-benzodioxol-5-yl)-1-ethanones, (X = Cl, Br, N 3) by Rhodothorula glutinis CCT 2182 afforded the corresponding (R)-ethanols in good to excellent yields (57-99%) and excellent enantiomeric excesses (>99%). These alcohols may be used as raw materials for the preparation of the pharmaceuticals (R)-(-)-epinephrine, (R)-(-)-norepinephrine and (R)-(-)-isoproterenol. © 2004 Elsevier Ltd. All rights reserved.
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Rights: fechado
Identifier DOI: 10.1016/j.tetasy.2004.07.029
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-4444358166&partnerID=40&md5=a072bb8e65df95b803e9ca893de843f9
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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