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|Type:||Artigo de periódico|
|Title:||Lack Of Arg972 Polymoyphism In The Irs1 Gene In Parakanã Brazilian Indians|
|Abstract:||Several polymorphisms in the insulin receptor substrate-1 (IRS1) gene have been reported in the last years. The most common IRS1 variant, a Gly → Arg substitution at codon 972 (Arg972 IRS1), is more prevalent among subjects who have features of insulin resistance syndrome associated, or not, with type 2 diabetes in European populations. To determine whether the absence of IRS1 polymorphism is a more general characteristic of Paleo-Indian-derived populations, we examined the Arg972 IRS1 polymorphism in Parakanã Indians and found a lack of this polymorphism in the Parakanã population.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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