Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/94357
Type: Artigo de periódico
Title: Lack Of Arg972 Polymoyphism In The Irs1 Gene In Parakanã Brazilian Indians
Author: Bezerra R.M.N.
Chadid T.T.
Altemani C.M.
Sales T.S.I.
Menezes R.
Soares M.C.P.
Saad S.T.O.
Saad M.J.A.
Abstract: Several polymorphisms in the insulin receptor substrate-1 (IRS1) gene have been reported in the last years. The most common IRS1 variant, a Gly → Arg substitution at codon 972 (Arg972 IRS1), is more prevalent among subjects who have features of insulin resistance syndrome associated, or not, with type 2 diabetes in European populations. To determine whether the absence of IRS1 polymorphism is a more general characteristic of Paleo-Indian-derived populations, we examined the Arg972 IRS1 polymorphism in Parakanã Indians and found a lack of this polymorphism in the Parakanã population.
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Rights: fechado
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Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-2942666216&partnerID=40&md5=bae9b8a942233acf6509ec9730c1de79
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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