Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/94330
Type: Artigo de periódico
Title: Prevalence Of Pulmonary Hypertension In Systemic Sclerosis [avaliação Da Prevalência De Hipertensão Pulmonar Na Esclerose Sistêmica]
Author: de Azevedo A.B.C.
Sampaio-Barros P.D.
Torres R.M.
Moreira C.
Abstract: Objective: To assess the prevalence of pulmonary arterial hypertension (PAH) in patients with diagnosis of systemic sclerosis (SSc) evaluated at a university tertiary service. Methods: Fifty-seven SSc patients attending the Rheumatology outpatient clinic of HC-UFMG were studied by clinical assessment addressed to cardiopulmonary system, pulmonary function tests and Doppler echocardiography (ECO). The following criteria were considered for the diagnosis of PAH: pulmonary arterial systolic pressure (PASP) ≥ 40mmHg and/or the presence of direct or indirect signs of PAH found during the ECO. Results: Sixteen patients (28%) were found to have the diagnosis of PAH at ECO, 13 with PASP ≥ 40mmHg and 3 with direct and indirect signs of PAH; 8 patients had isolated PAH and 8, PAH secondary to pulmonary fibrosis. Nine patients had suggestive signs of cor pulmonale at ECO; 6 of these patients presented PASP ≥ 40mmHg and 3 PASP between 35 and 40mmHg; 1 of them was not symptomatic and 8 had clinical exam suggestive of PAH. Regarding the clinical and laboratory variables studied, it was observed statistical association between PAH and elevated erythrocyte sedimentation rate (ESR) (p = 0,004). Conclusions: There was a prevalence of PAH in SSc similar to that observed in the literature, in spite of limitations in this comparison. The assessment of PAH by ECO is accessible and practical; however, it is necessary to review the cut off of the PASP levels considered for the diagnosis of PAH in SSc, especially when considering an early diagnosis.
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Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-55449120724&partnerID=40&md5=1ba2e8fce3c9f072ecf9eb0f6c4700af
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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