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|Type:||Artigo de periódico|
|Title:||Genetic Studies Suggest A Novel Portuguese Origin For Hemoglobin Porto Alegre|
Ferreira Costa F.
|Abstract:||Molecular studies performed in Portuguese and Brazilian cases of hemoglobin Porto Alegre [β9 Ser→Cys]Cy's revealed that the mutation is in association with the Mediterranean haplotype I and framework 1 and that it is also in cis with an undescribed intragenic polymorphism (codon 27, GCC→GCT). Based upon these findings, and reinforced by historical data, we suggest that hemoglobin Porto Alegre originated from a single mutational event in the Portuguese population and was then spread to South America, namely to Brazil.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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