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Type: Artigo de periódico
Title: Prevalence Of Helicobacter Pylori In Advanced Gastric Stump Cancer [prevalência Do "helicobacter Pylori" Em Pacientes Com Câncer De Coto Gástrico Avançado]
Author: Andreollo N.A.
Lopes L.R.
De Sousa Pimenta D.
De Souza Coelho Neto J.
Stedile J.A.G.
Abstract: Helicobacter pylori (Hp) has been mentioned as one of the main agents in the etiology of gastric cancer and also of gastric stump cancer. The purpose of this study was to assess the Hp infection prevalence in surgical specimens resected from 25 patients with gastric stump neoplasm submitted to total gastrectomy or degastrectomy, and to relate this information with the following variables: age, gender, ethnic group, symptoms, period between the initial surgery and the diagnosis of neoplasm, and the surgical technique performed (Billroth I or Billroth II). Hp was found in 8 patients (32%), 7 with more than 50 years of age, 6 male, and all of them with Billroth II reconstruction (p < 0.05). The interval between the initial surgery and the neoplasia in Hp+ patients was 28.7 years (p > 0.05). As to the other correlations between the presence of Hp and ethnic group, previous location of the ulcer (gastric or duodenal), interval between the initial gastrectomy and the gastric stump cancer, and histopathology of the tumor, none was significant (p > 0.05). The final conclusions are that the occurrence of Hp in gastric stump cancer is not high. Besides, although the bile-pancreatic and intestinal reflux, nutrition, and environmental factors such as the action of nitrites, nitrates, and N-nitrous compounds are the more important current factors, the participation of this microorganism in the etiopathogeny of this disease cannot be disregarded.
Rights: fechado
Identifier DOI: 
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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