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Type: Artigo de periódico
Title: Discrimination Between Normal And Glaucomatous Eyes By Scanning Laser Polarimetry [discriminação Entre Olhos Normais E Glaucomatosos Mediante Polarimetria De Varredura A Laser]
Author: Magacho L.
Marcondes A.M.
Costa V.P.
Abstract: Purpose: To test the ability of the scanning laser polarimetry to discriminate between normal and glaucomatous eyes. Methods: One-hundred and twelve patients with primary open-angle glaucoma and 88 normal individuals were enrolled in the study. All individuals underwent a complete ophthalmic evaluation, a 24-2 full threshold Humphrey visual field and a GDx examination. Cutoff points were selected, ROC curves were created, and the sensitivity (Se) and specificity (Sp) were calculated for each individual GDx parameter. Finally, a multivariate logistic analysis was developed in order to achieve a better Se/Sp ratio for the diagnosis of glaucoma. Results: The best GDx individual parameters were: the number (Se: 79.5%%, Sp: 81.8%, area under the ROC curve: 0.870), maximum modulation (Se: 83.0%, Sp: 76.1%, area under the ROC curve: 0.842) and ellipse modulation (Se: 65.2%, Sp: 88.6%). The multivariate logistic analysis resulted in an area under the ROC curve of 0.920 (Se: 85.7%, Sp: 90.9%). Conclusions: The combination of 2 or more parameters in a multivariate logistic analysis increases the ability of scanning laser polarimetry to discriminate between normal and glaucomatous eyes.
Rights: aberto
Identifier DOI: 
Date Issue: 2004
Appears in Collections:Unicamp - Artigos e Outros Documentos

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