Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/93388
Type: Artigo de periódico
Title: Characterisation Of A New Splice Variant Of Mask-bp3arf And Mask Human Genes, And Their Expression Patterns During Haematopoietic Cell Differentiation
Author: Duarte A.D.S.S.
Traina F.
Favaro P.M.B.
Basseres D.S.
De Carvalho I.C.
Medina S.D.S.
Costa F.F.
Saad S.T.O.
Abstract: In this study we report the characterisation of a new splice variant, here denominated splice variant 4 (accession number AF258557) of the human Multiple Ankyrin repeats Single KH domain (hMASK) (accession number AF521882) and the hMASK-4E-Binding Protein 3 Alternative Reading Frame (hMASK-BP3ARF) (accession number AF521883), containing a number of ANK-repeat motifs. Ankyrin (ANK) repeat-containing proteins carry out a wide variety of biological activities and are involved in processes, such as cell differentiation and transcriptional regulation. The present study reports the computer analysis of these splice variant cDNAs and their broad mRNA expression in different normal human tissues and cancer cell lines. An upregulation of the splice variant mRNAs expression was observed after HL-60 and erythroblast differentiation. The upregulation of splice variant 4 mRNA was considerably higher than those of the other variants, during erythroid differentiation. © 2005 Elsevier B.V. All rights reserved.
Editor: 
Rights: fechado
Identifier DOI: 10.1016/j.gene.2005.08.002
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-28044441879&partnerID=40&md5=627db27611f96b093dc52a1b4981398c
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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