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Type: Artigo de periódico
Title: Genes Involved In Sex Determination And Differentiation [genes Envolvidos Na Determinação E Diferenciação Do Sexo.]
Author: Mello M.P.
Assumpcao J.G.
Hackel C.
Abstract: Chromosomal sex is established at fertilization by the presence of an X or Y chromosome. The first step of male and female development is gonadal specialization in testes or ovaries; all other processes that follow result from secondary effects produced by testis and ovary hormones. Gonadal determination and differentiation and the development of external genitalia involve time- and tissue-specific expression of genes forming a gene cascade. Those genes, their expression profile and their role in the pathological manifestations related to gonadal and external genitalia development will be discussed in this review.
Rights: aberto
Identifier DOI: 
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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