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|Type:||Artigo de periódico|
|Title:||Genes Involved In Sex Determination And Differentiation [genes Envolvidos Na Determinação E Diferenciação Do Sexo.]|
|Abstract:||Chromosomal sex is established at fertilization by the presence of an X or Y chromosome. The first step of male and female development is gonadal specialization in testes or ovaries; all other processes that follow result from secondary effects produced by testis and ovary hormones. Gonadal determination and differentiation and the development of external genitalia involve time- and tissue-specific expression of genes forming a gene cascade. Those genes, their expression profile and their role in the pathological manifestations related to gonadal and external genitalia development will be discussed in this review.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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