Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/93119
Type: Artigo de periódico
Title: Clinical Assessment Of Efficacy And Safety From Cordia Verbenacea Standartized Extract In Tendinitis And Chronical Miofacial Pain Patients [avaliação Clínica Da Eficácia E Segurança Do Uso De Extrato Padronizado Da Cordia Verbenacea Em Pacientes Portadores De Tendinite E Dor Miofascial]
Author: Refsio C.
Brandao D.D.C.
Brandao G.D.C.
Korukian M.
Garcia R.J.
Bonfiglioli R.
De Souza Nery C.A.
Gamba R.
Abstract: The cream of Cordia verbenacea was evaluated regarding efficacy and use safety in 459 subjects (phase I+II+III). The achieved results related to the use safety of the medicine topically applied on different areas of skin integument, showed excellent tolerability of the product, clinically confirming the results achieved on preclinical toxicological studies(4,10,11,12). There was only one report of adverse event observed in one patient treated with cream of Cordia verbenacea with possible causal relation to the medicine (increase of sensibility), while the other 5 reports of adverse events in this group did not show relation to the drug. In the control group (diclofenaco dietilamônio), 15 occurrences of adverse events were reported, 4 of them were probably associated with the drug (cephalea, epigastralgia, vermilion, and pock on the area of application). The cream of Cordia verbenacea was evaluated regarding efficacy, on myofascial pain and tendinitis treatment, in 169 patients. 171 patients treated with diclofenaco dietilamônio 1% gel, were used as a control group. The same dose regimen was administered to both groups (topical use - 3 times a day). The distribution of the affections studied was also equally divided between both groups. The results referring to the use of the medicine topically applied on different areas of the body demonstrated excellent efficacy on the treatment of the evaluated musculoskeletal affections. According to all information presented in this report, in which the excellent efficacy and tolerability of the cream of Cordia verbenacea 0,5% gel was demonstrated, this product may be considered a progress and an important contribution for the therapeutic arsenal of muscoeskeletal affections where inflammatory processes exist. © Copyright Moreira Jr. Editora.
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Rights: fechado
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Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-16444381569&partnerID=40&md5=41786f5cc02388cdaa8bacf0fd0c0ca6
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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