Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/92742
Type: Artigo de periódico
Title: Study Of Morphology Of Cardiac Valves (human And Bovine Pericardium) After In Vivo Calcification
Author: Nogueira G.M.
Aimoli C.G.
Weska R.F.
Leirner A.A.
Maizato M.J.S.
Higa O.Z.
Polakiewicz B.
Pitombo R.N.M.
Beppu M.M.
Abstract: Pathologic calcification can lead to failure or deterioration of cardiac valves. Several researchers have tried alternatives to construct these devices, such as the incorporation or utilization of new biomaterials able to inhibit or decrease the calcification process. In vitro calcification tests can be used to screen new biomaterials regarding their potential to calcify in vivo. However, the mechanisms involved in both cases are not completely understood. In order to collect more information about the calcification process of implanted materials, morphology and elemental analyses of calcified cardiac valve fragments explanted from different patients were investigated and compared to previous reports of in vitro calcification tests. Scanning Electron Microscopy (SEM) and energy dispersive spectroscopy (EDS) analyses indicated that the calcium phosphate deposits from both bovine pericardium and human cardiac valves calcified in vivo were similar to the deposits obtained from in vitro calcification samples as previously reported in the literature.
Editor: 
Rights: fechado
Identifier DOI: 10.4028/0-87849-353-0.191
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-58849142224&partnerID=40&md5=82344d39316774682c3cf2497c8826e9
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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