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Type: Artigo de periódico
Title: Preoperative Pelvic Lymphoscintigraphy Is Of Limited Usefulness For Sentinel Lymph Node Detection In Cervical Cancer
Author: Vieira S.C.
Sousa R.B.
Tavares M.B.A.C.
Silva J.B.
Abreu B.A.L.
Santos L.G.
da Silva B.B.
Zeferino L.C.
Abstract: Objectives: To analyze concordance between preoperative lymphoscintigraphy and intraoperative lymphatic mapping (ILM) for sentinel lymph node identification using technetium 99m-labeled-dextran 500 (99m-Tc) and patent blue dye in patients with early cervical cancer undergoing radical hysterectomy and pelvic lymphadenectomy, as well as to evaluate sentinel lymph node (SLN) detection. Study design: Forty-seven patients underwent surgical treatment for cervical cancer. For SLN identification, 99m-Tc and blue patent were injected into the cervix on the eve and day of surgery, respectively. Preoperative pelvic lymphoscintigraphy was performed in all patients after 99m-Tc injection. Concordance between preoperative lymphoscintigraphy and ILM was evaluated. Results: Of the 56 patients who underwent preoperative lymphoscintigraphy, 43 (81.13%) had at least one lymph node identified. Bilateral lymph nodes were identified in 21 (37.5%) patients. Sentinel lymph nodes detected on ILM had been previously found on preoperative lymphoscintigraphy in 66.7%, 67.2% and 0% in the right, left and central locations, respectively. In 14 patients (25%), only one lymph node was identified on preoperative lymphoscintigraphy, but more than one sentinel lymph node was detected on intraoperative mapping. In nine (16.1%) patients, lymphoscintigraphy showed only unilateral lymph nodes, but ILM identified bilateral sentinel lymph nodes. Conclusion: The combination of patent blue and radionuclide techniques produced excellent results for SLN detection in cervical cancer. Preoperative lymphoscintigraphy does not offer any advantage over ILM for SLN identification. © 2009 Elsevier Ireland Ltd. All rights reserved.
Rights: fechado
Identifier DOI: 10.1016/j.ejogrb.2009.03.025
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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