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Type: Artigo de periódico
Title: New Mechanisms By Which Physical Exercise Improves Insulin Resistance In The Skeletal Muscle [novos Mecanismos Pelos Quais O Exercício Físico Melhora A Resistência à Insulina No Músculo Esquelético]
Author: Pauli J.R.
Cintra D.E.
de Souza C.T.
Ropelle E.R.
Abstract: Insulin resistance of skeletal muscle glucose transport is a key-defect for the development of impaired glucose tolerance and type 2 diabetes. However, it is known that both an acute bout of exercise and chronic endurance exercise training can bring beneficial effects on insulin action in insulin-resistant states. However, little is currently known about the molecular effects of acute exercise on muscle insulin signaling in the post-exercise state in insulin-resistant organisms. This review provides new insight into the mechanism through which acute exercise restores insulin sensitivity, highlighting an important role for inflammatory proteins and S-nitrosation in the regulation of insulin signaling proteins in skeletal muscle.
Rights: aberto
Identifier DOI: 
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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