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|Type:||Artigo de periódico|
|Title:||New Mechanisms By Which Physical Exercise Improves Insulin Resistance In The Skeletal Muscle [novos Mecanismos Pelos Quais O Exercício Físico Melhora A Resistência à Insulina No Músculo Esquelético]|
de Souza C.T.
|Abstract:||Insulin resistance of skeletal muscle glucose transport is a key-defect for the development of impaired glucose tolerance and type 2 diabetes. However, it is known that both an acute bout of exercise and chronic endurance exercise training can bring beneficial effects on insulin action in insulin-resistant states. However, little is currently known about the molecular effects of acute exercise on muscle insulin signaling in the post-exercise state in insulin-resistant organisms. This review provides new insight into the mechanism through which acute exercise restores insulin sensitivity, highlighting an important role for inflammatory proteins and S-nitrosation in the regulation of insulin signaling proteins in skeletal muscle.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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