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|Type:||Artigo de periódico|
|Title:||Occurrence Of Polycyclic Aromatic Hydrocarbons Derivatives And Mutagenicity Study In Extracts Of Pm10 Collected In São Paulo, Brazil|
De Carvalho L.R.F.
|Abstract:||Nitro-PAH and oxy-PAH fractions in organic extracts of PM10 collected in São Paulo City, Brazil (winter, 2004) were chemically and toxicologically analyzed. Some nitro- PAH compounds that are emitted from vehicular motor exhaust were quantified. The 3-nitrofluoranthene, which probably coeluted with the 2-nitrofluoranthene, a secondary pollutant, presented higher levels (average: 0.16 ng m-3; maximum concentration: 0.26 ng m -3) than 1-nitropyrene (average: 0.031 ng m-3; maximum concentration: 0.054 ng m-3). No detectable amount of 6-nitrocrysene was found. Oxy-PAH compounds were not detected probably because they were present at concentrations much low. Both nitro- and oxy-PAH fractions have showed a similar frameshift mutagenic response with a higher potency in the absence of S9 compared to that in the presence of S9, indicating the prevalence of direct-acting compounds for the Salmonella/ microsome assay. The responses observed for the YG1041 strain (up to 1200 revertants μg-1) were significantly higher than for the TA98 (up to 28 revertants μg-1) indicating the presence of nitroaromatic compounds. At last, the presence of highly mutagenic compounds in the nitro-PAH fractions and oxygenated compounds containing NO2 radical in the oxy-PAH fraction was evidenced. ©Sociedade Brasileira de Toxicologia.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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