Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/91175
Type: Artigo de periódico
Title: Factors Associated With Infant Death After Apparent Life-threatening Event (alte)
Author: Romaneli M.T.D.N.
Fraga A.M.A.
Morcillo A.M.
Tresoldi A.T.
Baracat E.C.E.
Abstract: Objective: To detect factors associated with greater risk of death in infants after an apparent life-threatening event (ALTE). Methods: This cross-sectional, retrospective, descriptive and analytic study evaluated infants younger than 12 months who had a sudden event of cyanosis, pallor, hypotonia or apnea and were seen in the emergency department of a tertiary university hospital. Forward stepwise logistic regression (Wald) was used to calculate and adjust odds ratios to evaluate associations. Results: Mean age of the 145 patients included in the study was 105 days (median = 65 days). Eleven (7.6%) died, and their mean age was 189 days (median = 218 days). Mean age of survivors was 98 days (median = 62 days) (p = 0.003). Activity before the event, prematurity and number of events were not associated with death. A significant association was found with pallor. Of the 11 infants, 3 had spontaneous resolution of ALTE, whereas 8 patients [27.6%; p < 0.001; OR = 14.3 (95%CI 3.51-58.3)] did not. The associations with respiratory or cardiovascular disease were also significant. In multivariate analysis, immediate spontaneous resolution [p = 0.015; OR = 6.06 (95%CI 1.02-35.94)] and diagnosis of cardiovascular disease [p = 0.047; OR = 164.27 (95%CI 7.34-3.673.78)] remained statistically significant. Conclusion: Infants who experienced an ALTE had a higher risk of subsequent death when their age was greater than 6 months and the event had a long duration, particularly when ALTE was associated with cardiovascular disease. Copyright © 2010 by Sociedade Brasileira de Pediatria.
Editor: 
Rights: aberto
Identifier DOI: 10.2223/JPED.2045
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-78650164641&partnerID=40&md5=9bdfa6803bdc40bc0737f48651973f25
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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