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Type: Artigo de periódico
Title: Essential Oil Of Thymus Vulgaris: Preparation Of Pharmaceutical Mouthwash Formulation And In Vitro Evaluation Of The Bacterial Plaque-inhibiting Properties [Óleo Essencial De Thymus Vulgaris: Elaboração De Enxaguatório Bucal E Avaliação Do Efeito In Vitro Na Formação Da Placa Bacteriana]
Author: Santos R.I.
Pereira D.F.A.
Teodoro G.R.
Del Ciampo J.O.
Ogasawara M.S.
Canettieri A.C.V.
Khouri S.
Salvador M.J.
Abstract: The aim of this study was to evaluate the in vitro effect of the essential oil of Thymus vulgaris (thyme) pure or incorporate in a alcohol-free pharmaceutical mouth-wash formulation, against Streptococcus mutans (ATCC 25175), being determined the Minimal Inhibitory Concentration (MIC) and the effect in the bacterial plate formation. The MIC value obtained for the essential oil was 100 μg/mL (1%). The mouthwash pharmaceutical formulation containing commercial essential oil of T. vulgaris was preparated. Microbiological and macroscopic analysis as well as analyses for MEV confirmed the effectiveness of this new alcohol-free mouthwash formulation containing essential oil of T. vulgaris as agent with plaque-inhibiting properties and possible application in the preventive dentistry. The chemical characterization of the bioactive essential oil was accomplished by CG-MS, being verified the presence of carvacrol, p-cimene and α-pinene as major constituents.
Rights: fechado
Identifier DOI: 
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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