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Type: Artigo de periódico
Title: Exercise-induced Bronchospasm In Obese And Non-obese Asthmatic Adolescents [broncoespasmo Induzido Pelo Exercício Em Adolescentes Asmáticos Obesos E Não-obesos]
Author: Lopes W.A.
Leite N.
Rosario N.
Abstract: Objective: To assess and compare the frequency and severity of exercise-induced bronchospasm (EIB) in obese and non-obese asthmatic adolescents. Methods: Cross-sectional and descriptive study with 39 subjects aged ten to 16 years of both genders divided into two groups according to clinical history of asthma and/or allergic rhinitis and body mass index, as follows: asthmatic obese (n=18) and asthmatic non-obese (n=21). An exercise bronchoprovocation test was applied to diagnose EIB and was considered positive if the forced expiratory volume in one second (FEV1) decreased ≥15% in relation to pre-exercise FEV1. Maximum percent of fall in FEV1 (MF%FEV1) and the area above the curve (AAC 0-30) were calculated to evaluate the intensity and recovery of EIB. Fisher exact test was used to compare the frequency of EIB and Mann-Whitney test to compare the severity and recovery of EIB. Null hypothesis was rejected when p<0.05. Results: No significant difference was found in the frequency of EIB between the asthmatic obese (50%) and non-obese (38%) adolescents. However, the MF%FEV1 and AAC0-30 were significantly higher in the asthmatic obese as compared to the asthmatic non-obese patients (respectively, 37.7% and 455 versus 24.5% e 214, p≤0.03). Conclusions: Obesity did not contribute to the increase of the frequency of EIB in asthmatic and non-asthmatic patients. However, obesity contributed to the increase of severity and recovery time of EIB in asthmatics.
Rights: aberto
Identifier DOI: 10.1590/S0103-05822010000100007
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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