Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/90534
Type: Artigo de periódico
Title: Heck-matsuda Arylation As A Strategy To Access Kavalactones Isolated From Polygala Sabulosa, Piper Methysticum, And Analogues
Author: Soldi C.
Moro A.V.
Pizzolatti M.G.
Correia C.R.D.
Abstract: Herein, we describe the total syntheses of three bioactive pyrones isolated from Polygala sabulosa (i.e., 1, 4, and 7) and eight isolated from Piper methysticum (i.e., 8-10, 13, 15, and 18-20) using the Heck-Matsuda arylation as the key strategy. The evaluation of this methodology by employing different arenediazonium tetrafluoroborates revealed that the Heck arylation was more efficient when the olefin undergoing arylation possessed the vinyl-2-pyrone structural unit instead of the vinyl dihydro-2-pyrone moiety. The Heck-Matsuda arylation of many of the examined olefins proceeded in a practical manner with total regio- and stereocontrol. © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Editor: 
Rights: fechado
Identifier DOI: 10.1002/ejoc.201200308
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-84862742692&partnerID=40&md5=b6670452e9ad1a83ee9c8d07b924c89e
Date Issue: 2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

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