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Type: Artigo de periódico
Title: Spontaneous Puberty In Girls With Early Diagnosis Of Turner Syndrome [puberdade Espontânea Em Meninas Com Diagnóstico Precoce De Síndrome De Turner]
Author: Carpini S.
Carvalho A.B.
Guerra-Junior G.
Matias Baptista M.T.
Lemos-Marini S.H.V.
Maciel-Guerra A.T.
Abstract: Objective: To verify if the frequency of spontaneous pubertal development among girls with Turner syndrome (TS) diagnosed in infancy and childhood is greater than that of patients diagnosed later. Subjects and methods: Thirty three girls aged < 10 years at the time of diagnosis were evaluated regarding pubertal development. The frequency of spontaneous puberty was compared with that of girls aged > 13 years diagnosed at the same service. Results: Sixteen of 32 informative patients had signs of spontaneous puberty, a frequency greater than that of patients diagnosed later. In six patients, there was no progression of puberty; menarche occurred in six, and one became pregnant, but the fetus was a stillborn. Spontaneous puberty was absent in all cases with 45,X karyotype. Conclusions: The greater prevalence of spontaneous puberty in girls whose diagnosis was not based on pubertal delay suggests that, among those diagnosed later, there is a bias towards patients with hypogonadism. © ABE&M todos os direitos reservados.
Rights: aberto
Identifier DOI: 10.1590/S0004-27302012000900009
Date Issue: 2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

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