Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/89311
Type: Artigo de periódico
Title: Acidulated Phosphate Fluoride Application Changes The Protein Composition Of Human Acquired Enamel Pellicle.
Author: Masson N.
Domingues R.R.
Cury J.A.
Paes Leme A.F.
Abstract: We evaluated, by proteomic analysis, whether the chemical changes provoked on enamel by acidulated phosphate fluoride (APF) application alter the protein composition of acquired enamel pellicle. Enamel slabs, pretreated with distilled water (negative control), phosphoric acid (active control) or APF solution, were immersed in human saliva for pellicle formation. The adsorbed proteins were extracted and analyzed by liquid chromatography-mass spectrometry/mass spectrometry. Fifty-six proteins were identified, 12 exclusive to APF and 11 to phosphoric acid. APF decreased the concentration of histatin-1, but increased the concentration of S100-A9, which is confirmed by immunoblotting. The findings suggest that APF application changes the acquired enamel pellicle composition. Copyright © 2013 S. Karger AG, Basel.
Editor: 
Rights: fechado
Identifier DOI: 10.1159/000346280
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-84872772503&partnerID=40&md5=eec3d219889de6a45317c35225e57f1a
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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