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Type: Artigo de periódico
Title: Myocardial Perfusion Scintigraphy In The Detection Of Silent Ischemia In Asymptomatic Diabetic Patients [cintilografia De Perfusão Miocárdica Na Detecção Da Isquemia Silenciosa Em Pacientes Diabéticos Assintomáticos]
Author: Oki G.C.R.
Pavin E.J.
Coelho O.R.
Parisi M.C.R.
Almeida R.C.
Etchebehere E.C.S.C.
Camargo E.E.
Ramos C.D.
Abstract: Objective: This study was aimed to evaluate myocardial perfusion in asymptomatic patients with type 1 (DM1) and type 2 diabetes mellitus (DM2) without previous diagnoses of coronary artery disease (CAD) or cerebral infarction. Materials and Methods: Fifty-nine consecutive asymptomatic patients (16 DM1, 43 DM2) underwent myocardial perfusion scintigraphy with 99mTc-sestamibi (MPS). They were evaluated for body mass index, metabolic control of DM, type of therapy, systemic arterial hypertension, dyslipidemia, nephropathy, retinopathy, peripheral neuropathy, smoking, and familial history of CAD. Results: MPS was abnormal in 15 patients (25.4%): 12 (20.3%) with perfusion abnormalities, and 3 with isolated left ventricular dysfunction. The strongest predictors for abnormal myocardial perfusion were: age 60 years and above (p = 0.017; odds ratio [OR] = 6.0), peripheral neuropathy (p = 0.028; OR = 6.1), nephropathy (p = 0.031; OR = 5.6), and stress ECG positive for ischemia (p = 0.049; OR = 4.08). Conclusion: Silent myocardial ischemia occurs in more than one in five asymptomatic diabetic patients. The strongest predictors of ischemia in this study were: patient age, peripheral neuropathy, nephropathy, retinopathy and a stress ECG positive for ischemia. © Colégio Brasileiro de Radiologia e Diagnóstico por Imagem.
Rights: aberto
Identifier DOI: 10.1590/S0100-39842013000100007
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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