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Type: Artigo de periódico
Title: Urinary Dysfunction With Detrusor Hyperactivity In Women With Parkinson's Disease Cannot Be Blamed As A Factor Of Worsening Motor Performance [disfunção Urinária Com Hiperatividade Detrusora Não é Fator De Risco Para Progressão Do Desempenho Motor Em Mulheres Com Doença De Parkinson]
Author: Campos-Sousa R.N.
Quagliato E.M.A.B.
Almeida K.J.
de Castro I.A.D.
Campelo V.
Abstract: Introduction: Detrusor hyperactivity is the leading cause of urinary dysfunction in Parkinson's disease (PD). There are few studies correlating PD clinical aspects with this autonomic feature. Methods: A cohort of 63 women with PD were prospectively examined for assessment of clinical aspects and disease severity using unified Parkinson's disease rating scale and Hoehn-Yahr scale, respectively. The urologic function was evaluated by the urodynamic study. Two groups were categorized at this time - groups with and without detrusor hyperactivity. After seven years, the same parameters were re-evaluated. Results: Progression of the disease on mental scores was found in the group with detrusor hyperactivity. On follow-up, clinical symptoms and severity did not show significant worsening between the groups. Conclusion: Detrusor hyperactivity is a frequent urodynamic finding in PD, and even though it is associated with dopaminergic dysfunction, it cannot be blamed as a factor of worsening motor performance, but is probably associated with poor cognitive and mental prognosis.
Rights: aberto
Identifier DOI: 10.1590/0004-282X20130101
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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