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dc.typeArtigo de periódicopt_BR
dc.titleEvaluation Of Respiratory Impairment In Patients With Systemic Lupus Erythematosus With The Six-minute Walk Testpt_BR
dc.contributor.authorLeite M.A.pt_BR
dc.contributor.authorPereira M.C.pt_BR
dc.contributor.authorCostallat L.T.L.pt_BR
dc.contributor.authorVillalba W.O.pt_BR
dc.contributor.authorMoreira M.M.pt_BR
dc.contributor.authorPaschoal I.A.pt_BR
unicamp.authorLeite, M.A., Department of Internal Medicine, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazilpt_BR
unicamp.authorPereira, M.C., Department of Internal Medicine, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazilpt_BR
unicamp.authorCostallat, L.T.L., Department of Internal Medicine, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazilpt_BR
unicamp.authorVillalba, W.O., Department of Internal Medicine, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazilpt_BR
unicamp.authorMoreira, M.M., Department of Internal Medicine, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazilpt_BR
unicamp.authorPaschoal, I.A., Department of Internal Medicine, Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazilpt_BR
dc.description.abstractObjective: Evaluate SLE stable patients, without overt respiratory compromise, by means of 6MWT. Casuistic and methods: Forty-five stable SLE patients were enrolled. The ATS/ERS protocol for 6MWT, was used and two parameters with cut-off points were chosen. Results: Forty-two patients were women. The mean age was 39 ± 11.4 years; mean duration of disease, 121 ± 93.1 months; mean value of MRC, 2 ± 0; mean FVC, 85.9 ± 34.2%; mean FEV1, 67.5 ± 21.6%; mean MIP, 82 ± 58.4%; mean MEP, 78 ± 37.3%; mean heart rate at rest, 75 ± 12.8 bpm; mean respiratory rate at rest, 19 ± 5.3 bpm; mean 6MWD, 478 ± 82 m; mean SpO2 at rest was 98 ± 0.8%; mean fall in SpO2, 4 ± 6 points. When the study population was divided according to the 400-m walk distance cut-off value, the heart rate immediately before the test was significant lower in those participants who walked less than 400 m (p = 0.0043), just like the value of Borg scale (p = 0.0036); according to the presence of saturation ≥ 4, heart rate at the end of the test was significantly higher in those participants who were showing desaturation (p = 0.0170); MEP (p = 0.0282) and 6MWD (p = 0.0291) were significantly lower, and MIP showed a tendency towards being smaller (p = 0.0504). FVC < normal inferior limit was significantly associated with the group with desaturation (p = 0.0274). Conclusion: Compared to 6MWD, desaturation was better suited to find the patients with the most compromised indexes in respiratory function tests. © 2014 Sociedade Brasileira de Reumatologia. Published by Elsevier Editora Ltda. All rights reserved.en
dc.relation.ispartofRevista Brasileira de Reumatologiapt_BR
dc.publisherElsevier Editora Ltdapt_BR
dc.identifier.citationRevista Brasileira De Reumatologia. Elsevier Editora Ltda, v. 54, n. 3, p. 192 - 199, 2014.pt_BR
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dc.description.referenceRus, V., Maury, E.E., Hochberg, M.C., The epidemiology of systemic lupus erythematosus (2007) Dubois lupus erythematosus, pp. 34-44. , Wallace DJ, Hahn BH, editors. 7th ed. Filadélfia: Lippincott Williams & Wilkins;pt_BR
dc.description.referenceSato, E.I., Natour, J., Martinelli, V.P.L., Assis, L.S.S., Farão, S.R., Medeiros, E.L., Seguimento clínico e laboratorial de 132 pacientes com lúpus eritematoso sistêmico (1991) Rev Bras Reumatol, 31, pp. 57-62pt_BR
dc.description.referenceCostallat, L.T.L., Coimbra, A.M.V., Lúpus eritematoso sistêmico: análise clínica e laboratorial de 272 pacientes em um hospital universitario: 1973-1982 (1995) Rev Bras Reumatol, 35, pp. 23-29pt_BR
dc.description.referenceRothfield, N.F., Systemic lupus erythematosus: clinical aspects and treatment (1993), pp. 1155-1177. , McCarty DJ & Koopman WJ. Arthritis and allied conditions - a textbook of rheumatology, 12. ed. Philadelphia: Lea & FebigerBelmont, H.M., Abramson, S.B., Lie, J.T., Pathology and pathogenesis of vascular injury in systemic lupus erythematosus Interactions of inflammatory cells and activated endothelium. (1996) Arthritis Rheum, 39, pp. 9-22pt_BR
dc.description.referenceKrishnaswamy, G., Kelley, J., Yerra, L., Smith, J.K., Chi, D.S., Human endothelium as a source of multifunctional cytokines: molecular regulation and possible role in human disease (1999) J Interferon Cytokine Res, 19, pp. 91-104pt_BR
dc.description.referenceHochberg, M.C., Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus (1997) Arthritis Rheum, 40, p. 1725pt_BR
dc.description.referenceATS., statement: guidelines for the six-minute walk, test (2002) Am, J., Respir Crit Care Med, 166, pp. 111-117pt_BR
dc.description.referencePoulain, M., Durand, F., Palomba, B., Ceugniet, F., Desplan, J., Varray, A., 6-minute walk testing is more sensitive than maximal incremental cycle testing for detecting oxygen desaturation in patients with COPD (2003) Chest, 123, pp. 1401-1407pt_BR
dc.description.referenceKawut, S.M., Horn, E.M., Berekashvili, K.K., Garofano, R.P., Goldsmith, R.L., Widlitz, A.C., New predictors of outcome in idiopathic pulmonary arterial hypertension (2005) Am J Cardiol, 95, pp. 199-203pt_BR
dc.description.referenceMiyamoto, S., Nagaya, N., Satoh, T., Kyotani, S., Sakamaki, F., Fujita, M., Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension Comparison with cardiopulmonary exercise testing (2000) Am J Respir Crit Care Med, 161, pp. 487-492pt_BR
dc.description.referencePaciocco, G., Martinez, F.J., Bossone, E., Pielsticker, E., Gillespie, B., Rubenfire, M., Oxygen desaturation on the six-minute walk test and mortality in untreated primary pulmonary hypertension (2001) Eur Respir J, 17, pp. 647-652pt_BR
dc.description.referenceVillalba, W.O., Sampaio-Barros, P.D., Pereira, M.C., Cerqueira, E.M., Leme Jr, C.A., Marques-Neto, J.F., Six-minute walk test for the evaluation of pulmonary disease severity in scleroderma patients (2007) Chest, 131, pp. 217-222pt_BR
dc.description.referenceRostagno, C., Olivo, G., Comeglio, M., Boddi, V., Banchelli, M., Galanti, G., Prognostic value of 6-minute walk corridor test in patients with mild to moderate heart failure: comparison with other methods of functional evaluation (2003) Eur J Heart Fail, 5, pp. 247-252pt_BR
dc.description.referencePereira, C.A., Diretrizes para Testes de Função Pulmonar (2002) J Bras Pneumologia, p. 28pt_BR
dc.description.referenceKnudson, R.J., Lebowitz, M.D., Holberg, C.J., Burrows, B., Changes in the normal maximal expiratory flow-volume curve with growth and aging (1983) Am Rev Respir Dis, 127, pp. 725-734pt_BR
dc.description.referenceII Consenso de, DPOC. (2004) J Bras Pneumol, 30, pp. s1-s42pt_BR
dc.description.referenceAmerican Thoracic Society/European Respiratory, Society. ATS/ERS Statement on respiratory muscle testing (2002) Am J Respir Crit Care Med, 166, pp. 518-624pt_BR
dc.description.referenceNeder, J.A., Andreoni, S., Lerario, M.C., Nery, L.E., Reference values for lung function tests II. Maximal respiratory pressures and voluntary ventilation (1999) Braz J Med Biol Res, 32, pp. 719-727pt_BR
dc.description.referencePrefaut, C., Durand, F., Mucci, P., Caillaud, C., Exercise-induced arterial hypoxaemia in athletes: a review (2000) Sports Med, 30, pp. 47-61pt_BR
dc.description.referenceSoares, M.R., Pereira, C.A., Six-minute walk test: reference values for healthy adults in Brazil (2011) J Bras Pneumol, 37, pp. 576-583pt_BR
dc.description.referenceCote, C.G., Casanova, C., Marín, J.M., Lopez, M.V., Pinto-Plata, V., de Oca, M.M., Validation and comparison of reference equations for the 6-min walk distance test (2008) Eur Respir J, 31, pp. 571-578pt_BR
dc.description.referenceKadikar, A., Maurer, J., Kesten, S., The six-minute walk test: a guide to assessment for lung transplantation (1997) J Heart Lung Transplant, 16, pp. 313-319pt_BR
dc.description.referenceProvencher, S., Chemla, D., Hervé, P., Sitbon, O., Humbert, M., Simonneau, G., Heart rate responses during the 6-minute walk test in pulmonary arterial hypertension (2006) Eur Respir J, 27, pp. 114-120pt_BR
dc.description.referenceFrost, A.E., Langleben, D., Oudiz, R., Hill, N., Horn, E., McLaughlin, V., The 6-min walk test (6MW) as an efficacy endpoint in pulmonary arterial hypertension clinical trials: demonstration of a ceiling effect (2005) Vascul Pharmacol, 43, pp. 36-39pt_BR
dc.description.referenceLama, V.N., Flaherty, K.R., Toews, G.B., Colby, T.V., Travis, W.D., Long, Q., Prognostic value of desaturation during a 6-minute walk test in idiopathic interstitial pneumonia (2003) Am J Respir Crit Care Med, 168, pp. 1084-1090pt_BR
dc.description.referenceGibson, C.J., Edmonds, J.P., Hughes, G.R., Diaphragm function and lung involvement in systemic lupus erythematosus (1977) Am J Med, 63, pp. 926-932pt_BR
dc.description.referenceLaroche, C.M., Mulvey, D.A., Hawkins, P.N., Walport, M.J., Strickland, B., Moxham, J., Diaphragm strength in the shrinking lung syndrome of systemic lupus erythematosus (1989) Q J Med, 71, pp. 429-439pt_BR
dc.description.referenceEaton, T., Young, P., Milne, D., Wells, A.U., Six-minute walk, maximal exercise tests: reproducibility in fibrotic interstitial pneumonia (2005) Am J Respir Crit Care Med, 171, pp. 1150-1157pt_BR
dc.description.referenceNielsen, H.B., Arterial desaturation during exercise in man: implication for O2 uptake and work capacity (2003) Scand J Med Sci Sports, 13, pp. 339-358pt_BR
dc.description.referenceNielsen, H.B., Boesen, M., Secher, N.H., Near-infrared spectroscopy determined brain and muscle oxygenation during exercise with normal and resistive breathing (2001) Acta Physiol Scand, 171, pp. 63-70pt_BR
dc.description.referenceKikuchi, K., Kubo, M., Kadono, T., Yazawa, N., Ihn, H., Tamaki, K., Serum concentrations of vascular endothelial growth factor in collagen diseases (1998) Br J Dermatol, 139, pp. 1049-1051pt_BR
dc.description.referenceKuryliszyn-Moskal, A., Klimiuk, P.A., Sierakowski, S., Ciołkiewicz, M., Vascular endothelial growth factor in systemic lupus erythematosus: relationship to disease activity, systemic organ manifestation, and nailfold capillaroscopic abnormalities (2007) Arch Immunol Ther Exp (Warsz), 55, pp. 179-185pt_BR
dc.description.referenceGoldie, R.G., Endothelins in health and disease: an overview (1999) Clin Exp Pharmacol Physiol, 26, pp. 145-148pt_BR
dc.description.referenceBalsamo, S., Nascimento Dda, C., Tibana, R.A., De Santana, F.S., Da Mota, L.M., Dos Santos-Neto, L.L., The quality of life of patients with lupus erythematosus influences cardiovascular capacity in 6-minute walk test (2013) Rev Bras Reumatol, 53, pp. 75-87pt_BR
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