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Type: Artigo de periódico
Title: In Vitro Essay Analysis Of 50wt.% Ha-50wt.% Tio2 Composite Prepared By The Polymeric Sponge Method [análise De Ensaios In Vitro Do Compósito De 50% Ha-50% Tio2 Fabricados Pelo Método Da Esponja Polimérica]
Author: Galdino A.G.S.
Oliveira E.M.
Filippin-Monteiro F.B.
Zavaglia C.A.C.
Abstract: Once there is an increase on technology applied to human health, life expectancy has increased, but not all body parts can maintain their functions with aging process. Tissue engineering has developed for replacing, repairing or reconstructing lost or damaged tissues or organs by accidents or serious diseases through using and developing of new materials, which are biocompatible, bioabsorbable, porous, etc. This research aimed on evaluating in vitro essays of porous hydroxyapatite - titanium oxide (HA-TiO2) composite, with 50wt.% HA - 40wt.% TiO2 for using as scaffolds on bone tissue engineering. Samples have been made by the polymeric sponge method, using sodium bicarbonate as binder and flocculant. Sintering has been done at 1250 °C; 1300 °C and 1350 °C. Fibroblasts and osteoblasts immortalized lineages have been used to evaluate the composite cytotoxicity, cell adhesion and growth. Three samples were used for those essays at an interval of five days. Results have shown satisfactory, with fibroblasts and osteoblasts adhesion and growth, which serves as an indicator for the composite can be submitted to in vivo essays.
Editor: Associacao Brasileira de Ceramica
Rights: aberto
Identifier DOI: 
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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