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Type: Artigo de periódico
Title: Effect Of 4-(n,n-dimethylamino) Phenethyl Alcohol On Degree Of Conversion And Cytotoxicity Of Photo - Polymerized Cq - Based Resin Composites
Author: De Oliveira D.C.R.S.
Da Silva C.B.
Muniz B.V.
Volpato M.C.
Costa A.R.
Sinhoreti M.A.C.
Abstract: The aim of this study was to evaluate the degree of conversion (DC) and the cytotoxicity of photo-cured experimental resin composites containing 4-(N,N-dimethylamino) phenethyl alcohol (DMPOH) combined to the camphorquinone (CQ) compared with ethylamine benzoate (EDAB). The resin composites were mechanically blended using 35 wt% of an organic matrix and 65 wt% of filler loading. To this matrix was added 0.2 wt% of CQ and 0.2 wt% of one of the reducing agents tested. 5x1 mm samples (n=5) were previously submitted to DC measurement and then pre-immersed in complete culture medium without 10% (v/v) bovine serum for 1 h or 24 h at 37 °C in a humidifier incubator with 5% CO2and 95% humidity to evaluate the cytotoxic effects of experimental resin composites using the MTT assay on immortalized human keratinocytes cells. As a result of absence of normal distribution, the statistical analysis was performed using the nonparametric Kruskal-Wallis to evaluate the cytotoxicity and one-way analysis of variance to evaluate the DC. For multiple comparisons, cytotoxicity statistical analyses were submitted to Student-Newman-Keuls and DC analysis to Tukey’s HSD post-hoc test (α=0.05). No significant differences were found between the DC of DMPOH (49.9%) and EDAB (50.7%). 1 h outcomes showed no significant difference of the cell viability between EDAB (99.26%), DMPOH (94.85%) and the control group (100%). After 24 h no significant difference were found between EDAB (48.44%) and DMPOH (38.06%), but significant difference was found compared with the control group (p>0.05). DMPOH presented similar DC and cytotoxicity compared with EDAB when associated with CQ.
Editor: Associacao Brasileira de Divulgacao Cientifica
Rights: aberto
Identifier DOI: 10.1590/0103-6440201300113
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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