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Type: Artigo de periódico
Title: Disarray Of Glomerular And Tubular Cell Adhesion Molecules In The Course Of Experimental Bothrops Moojeni Envenomation
Author: Collares-Buzato C.B.
Cruz-Hofling M.A.D.
Abstract: In this study, we show that administration of Bothrops moojeni venom in rats induces a general disturbance in the distribution and content of the tight junctional protein ZO-1, the cell-matrix receptor beta 1 integrin, the cytoskeletal proteins, vinculin and F-actin, and of the extracellular matrix component laminin in renal corpuscles and cortical nephron tubules. These findings suggest that cell-cell and cell-matrix adhesion proteins may be molecular targets in the B. moojeni-induced kidney injury. © 2013 Published by Elsevier Ltd.
Editor: Elsevier Ltd
Rights: fechado
Identifier DOI: 10.1016/j.toxicon.2013.11.013
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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