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Type: Artigo
Title: Construction of 3-arylpropylamines using Heck arylations: the total synthesis of cinacalcet hydrochloride, alverine, and tolpropamine
Author: Prediger, Patrícia
Silva, Allan Ribeiro da
Correia, Carlos Roque Duarte
Abstract: New synthetic routes toward the commercial drugs cinacalcet hydrochloride, alverine, and tolpropamine were developed using a Heck–Matsuda arylation as the key-step. Several reaction conditions were evaluated for the Heck–Matsuda reaction using allylamine
Subject: Cloridrato de cinacalcete
Reação de Heck
Sais de arenodiazônio
Country: Reino Unido
Editor: Elsevier
Citation: Tetrahedron. Elsevier Ltd, v. 70, n. 20, p. 3333 - 3341, 2014.
Rights: Fechado
Identifier DOI: 10.1016/j.tet.2013.10.014
Date Issue: 2014
Appears in Collections:IQ - Artigos e Outros Documentos
FT - Artigos e Outros Documentos

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