Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/86869
Type: Artigo de periódico
Title: Phosphated Cellulose As An Efficient Biomaterial For Aqueous Drug Ranitidine Removal
Author: Bezerra R.D.S.
Silva M.M.F.
Morais A.I.S.
Osajima J.A.
Santos M.R.M.C.
Airoldi C.
Silva Filho E.C.
Abstract: Crystalline cellulose chemically modified through a reaction with sodium trimetaphosphate (STMP) in an acidic or basic condition yielded Cel-P4 and Cel-P10. These phosphated solids were characterized by elemental analysis, X-ray diffraction (XRD), infrared (IR) spectroscopy, scanning electron microscopy (SEM), nuclear magnetic resonance (NMR) at the solid state for phosphorus nucleus and dispersive X-ray energy. The elemental results demonstrated that the phosphorylation reaction was more efficient in the basic medium, as supported by the amount of phosphorous content. The synthesized biomaterials decreased in crystallinity in comparison to the precursor cellulose, with an increase in roughness and present two distinct phosphorus environments in the formed structure. The phosphated cellulose in an alkaline condition was applied to sorb the drug ranitidine. This process was applied in varying pH, time, temperature and concentration. The best sorption kinetic model to fit the experimental data was the pseudo-second-order with a coefficient correlation of 0.8976, and the Langmuir isotherm model was the most adjusted to the variation in concentration. The efficient drug sorption has a low dependence on temperature, with maximum values of 85.0, 82.0 mg and 85.7 mg.g-1 for Cel-P10 at 298, 308 and 318 K, respectively. The best sorption occurred at pH = 6 with a saturation time of 210 min.
Editor: MDPI AG
Rights: aberto
Identifier DOI: 10.3390/ma7127907
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-84921286474&partnerID=40&md5=e985e32be00d9c2cc3f7c56125cd76a1
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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