Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/86678
Type: Artigo
Title: The effect of fluoride toothpaste on root dentine demineralization progression: a pilot study
Author: Botelho, J. N.
Del Bel Cury, A. A.
Da Silva, W. J.
Tenuta, L. M. A.
Cury, J. A.
Abstract: The anticaries effect of fluoride (F) toothpaste containing 1100 μg F/g in reducing enamel demineralization is well established, but its effect on dentine has not been extensively studied. Furthermore, it has been shown that toothpaste containing a high F concentration is necessary to remineralize root dentine lesions, suggesting that a 1100 μg F/g concentration might not be high enough to reduce root dentine demineralization, particularly when dentine is subjected to a high cariogenic challenge. Thus, the aim of this pilot study was to evaluate in situ the effect of F toothpaste, at a concentration of 1100 μg F/g, on dentine demineralization. In a crossover and double-blind study, conducted in two phases of 14 days, six volunteers wore a palatal appliance containing four slabs of bovine root dentine whose surface hardness (SH) was previously determined and to which a 10% sucrose solution was applied extra-orally 8×/day. Volunteers used a non-F toothpaste (negative control) or F toothpaste (1100 μg F/g, NaF/SiO2) three times a day. On the 10th and 14th days of each phase, two slabs were collected and SH was determined again. Dentine demineralization was assessed as percentage of SH loss (%SHL). The effect of toothpaste was significant, showing lower %SHL for the F toothpaste group (42.0 ± 9.7) compared to the non-F group (62.0 ± 6.4; p < 0.0001), but the effect of time was not significant (p > 0.05). This pilot study suggests that F toothpaste at 1100 μg F/g is able to decrease dentine caries even under a high cariogenic challenge of biofilm accumulation and sugar exposure.
The anticaries effect of fluoride (F) toothpaste containing 1100 μg F/g in reducing enamel demineralization is well established, but its effect on dentine has not been extensively studied. Furthermore, it has been shown that toothpaste containing a high F concentration is necessary to remineralize root dentine lesions, suggesting that a 1100 μg F/g concentration might not be high enough to reduce root dentine demineralization, particularly when dentine is subjected to a high cariogenic challenge. Thus, the aim of this pilot study was to evaluate in situ the effect of F toothpaste, at a concentration of 1100 μg F/g, on dentine demineralization. In a crossover and double-blind study, conducted in two phases of 14 days, six volunteers wore a palatal appliance containing four slabs of bovine root dentine whose surface hardness (SH) was previously determined and to which a 10% sucrose solution was applied extra-orally 8×/day. Volunteers used a non-F toothpaste (negative control) or F toothpaste (1100 μg F/g, NaF/SiO2) three times a day. On the 10th and 14th days of each phase, two slabs were collected and SH was determined again. Dentine demineralization was assessed as percentage of SH loss (%SHL). The effect of toothpaste was significant, showing lower %SHL for the F toothpaste group (42.0 ± 9.7) compared to the non-F group (62.0 ± 6.4; p < 0.0001), but the effect of time was not significant (p > 0.05). This pilot study suggests that F toothpaste at 1100 μg F/g is able to decrease dentine caries even under a high cariogenic challenge of biofilm accumulation and sugar exposure
Subject: Dentina
Sacarose
Fluoretos
Biofilme
Cárie dentária
Country: Brasil
Editor: Sociedade Brasileira de Pesquisa Odontológica
Citation: Brazilian Oral Research. Sociedad Chilena De Enfermedades Respiratorias, v. 28, n. SPECIALISSUE, p. - , 2014.
Rights: aberto
Identifier DOI: 10.1590/S1806-83242014.50000007
Address: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242014000200003&lng=en&tlng=en
Date Issue: 2014
Appears in Collections:FOP - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
2-s2.0-84897973378.pdf1.56 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.