Please use this identifier to cite or link to this item:
|Type:||Artigo de periódico|
|Title:||Facts, Presumptions, And Myths On The Solvent-free And Catalyst-free Biginelli Reaction. What Is Catalysis For?|
De Oliveira A.L.
De Oliveira H.C.B.
Da Silva W.A.
|Abstract:||The current manuscript describes the role and importance of catalysis and solvent effects for the Biginelli multicomponent reaction. The overwhelming number of new catalysts and conditions recently published for the Biginelli synthesis, including in some manuscripts entitled catalyst-free and/or solvent-free have incentivized controversies and hot debates regarding the importance of developing new catalysts and reaction conditions to perform this very important multicomponent reaction. These so-called catalyst-free reports have generated much confusion in the field, requiring urgent elucidations. In this manuscript, we exemplify, demystify, and discuss the crucial role of catalysis, solvent effects, mechanisms, kinetics, facts, presumptions, and myths associated with the Biginelli reaction aiming to avoid current and future confusion and to stimulate new approaches. © 2014 American Chemical Society.|
|Editor:||American Chemical Society|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.